It has minimal side effects, and has been shown to be safe at up to 5 times the recommended dose. In a 90-day field study, 415 dogs were administered afoxolaner and no serious adverse reactions were observed with NexGard. The most frequent adverse reaction was vomiting, with 17 dogs experiencing that reaction.

NexGard® (afoxolaner) is for use in dogs only and is safe for dogs 8 weeks or older and weighing 4 pounds or more. The most frequently reported adverse reactions include vomiting, itching, lethargy, diarrhea, and lack of appetite. The safe use of NexGard in pregnant, breeding, or lactating dogs has not been evaluated.

Through it's rapid control of fleas, NexGard SPECTRA has been shown to be 100% effective at preventing flea tapeworm infestation for a full month however, it will not kill flea tapeworms that may already be present. To control existing tapeworm infestations use ParaGard Allwormer for Dogs.

Isoxazolines are neurotoxic to more than just insects; they also affect mammals. There is a reason why so many dogs experience seizures, ataxia, and tremors after taking NexGard - the pesticide compromises the dog's central nervous system. Once this happens, there is often no way back.

As you will see later in this article not treating your pet may actually be detrimental to its health. Merial, the manufacturer of Nexgard/Nexgard Spectra have advised us that they have no concerns about these products when used in healthy animals according to the data sheet.

Nexgard® Possible Side Effects Vomiting. Dry or itchy skin. Lethargy. Diarrhea.

These products are safe to use in the majority of pets, but there are some pets that cannot tolerate the medication (specific liver disorders, pre-existing seizure disorders).

In a separate well- controlled laboratory study, NexGard demonstrated 100% effectiveness against adult fleas 24 hours post-infestation for 35 days, and was ≥93% effective at 12 hours post-infestation through Day 21, and on Day 35. On Day 28, NexGard was 81.1% effective 12 hours post-infestation.

IMPORTANT SAFETY INFORMATION NexGard® (afoxolaner) is for use in dogs only and is safe for dogs 8 weeks or older and weighing 4 pounds or more. The most frequently reported adverse reactions include vomiting, itching, lethargy, diarrhea, and lack of appetite.

Causes of NexGard reactions in dogs are primarily due to a reaction to the active ingredient, afoxolaner. Specific causes include: The hypersensitivity towards the main ingredient. An over-reactive immune system.

NexGard is given as a tablet of the appropriate strength for the dog's bodyweight. NexGard kills fleas within 8 hours and ticks within 48 hours. After being given, its actions last for at least 5 weeks against fleas and up to one month against ticks.

Since the release of NexGard, adverse events that have been reported for dogs are listed here in decreasing order of reporting frequency: Vomiting, pruritus, lethargy, diarrhea (with and without blood), anorexia, seizure, hyperactivity/ restlessness, panting, erythema, ataxia, dermatitis (including rash, papules), ...