VIBERZI is a prescription medicine that is FDA approved for daily use in adults with IBS‑D to reduce abdominal pain and diarrhea at the same time. Taken every day as prescribed, VIBERZI may provide relief by making stools less loose and watery and reducing abdominal pain.

The most common side effects of VIBERZI include: constipation, nausea, and abdominal pain. Stop taking VIBERZI right away and immediately call your doctor if you have constipation that is severe. These are not all the possible side effects of VIBERZI.

IBS pain can occur anywhere from your chest down to your pelvis, where your main digestive organs are located. Upper abdomen pain: This often occurs with bloating and may be worse after meals. Middle abdomen pain: Cramps can occur around the area of the belly button.

Take with food. Viberzi may cause pancreatitis or constipation, which could be severe or lead to hospitalization. Call your doctor at once if you have severe or ongoing constipation, severe pain in your upper stomach spreading to your back (with or without nausea and vomiting).

Try any of the following things to help relieve IBS symptoms, or combine them as you please:

1. Apply Gentle Heat.
2. Get Moving.
3. Stay Away From Trigger Foods.
4. Have a Soothing, Non-Caffeinated Tea.
5. Dial Down Your Stress Levels.
6. Try a Relaxation Technique.

Medications to help cramping: Prescription meds like dicyclomine (Bentyl) and hyoscyamine (Levsin) have long been used to help treat the symptoms of IBS-D by slowing down your bowels to make bathroom visits less frequent and less painful.

VIBERZI can cause serious side effects, including: Stop taking VIBERZI and call your doctor if you have new or worsening stomach‑area (abdomen) pain or pain in the upper right side of your stomach‑area (abdomen) that may move to your back or shoulder, with or without nausea and vomiting.

Irritable Bowel Syndrome Types Mostly diarrhea and abdominal discomfort (IBS-D). Mostly constipation and abdominal discomfort (IBS-C). Alternating loose stools and constipation with abdominal discomfort (IBS-mixed).

If you have IBS, you can feel pain in different parts of your abdomen. The most common place to feel IBS pain is in your lower abdomen, but it can also be felt in your central abdomen, around your belly button. IBS pain is not usually experienced in the upper abdomen or stomach area.

In addition to stomach pain, you may notice your chest appearing bloated and full under your ribs. Your abdomen may feel very tender to the touch and may gurgle and make ample noise as your body struggles to work through the digestion of food intake.

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome): Dizziness. Gas. Nausea.

Medications approved for certain people with IBS include:

• Alosetron (Lotronex). Alosetron is designed to relax the colon and slow the movement of waste through the lower bowel.
• Eluxadoline (Viberzi).
• Rifaximin (Xifaxan).
• Lubiprostone (Amitiza).
• Linaclotide (Linzess).