While Heartgard Plus and Heartgard for dogs may sound similar, there is a fundamental difference between the two. While Heartgard offers protection against heartworm disease alone, Heartgard Plus tablets are effective against three types of worms, including heartworm, roundworm, and hookworm.

Heartgard Plus® is indicated for use in dogs to prevent canine heartworm disease by eliminating the tissue stage of heartworm larvae for a month (30 days) after infection, and for the treatment and control of roundworms and hookworms.

Boehringer Ingelheim Animal Health USA Inc.

Boehringer Ingelheim Animal Health USA Inc. HEARTGARD® is a registered trademark of Boehringer Ingelheim Animal Health USA Inc.

Heartworm treatment is expensive due to several factors: Heartworm medications are relatively new, and their high price is attributed to research and development costs. Moreover, the medication is often imported, making it more expensive to obtain.

monthly intervals HEARTGARD Plus should be given at monthly intervals during the period of the year when mosquitoes (vectors), potentially carrying infective heartworm larvae, are active. The initial dose must be given within a month (30 days) after the dog's first exposure to mosquitoes.

HEARTGARD® Plus (ivermectin/pyrantel) is well tolerated. The heartworm preventive in HEARTGARD Plus chews has been trusted over 2 billion times. HEARTGARD Plus is the #1 vet-recommended heartworm preventive.

IMPORTANT SAFETY INFORMATION: HEARTGARD Plus is well tolerated. All dogs should be tested for heartworm infection before starting a preventive program. Following the use of HEARTGARD Plus, digestive and neurologic side effects have been reported. For more information, click here for full prescribing information.

Boehringer Ingelheim Animal Health in recent years has expanded vaccine and drug factories in Georgia and Missouri. The 48-year-old Puerto Rico plant now manufactures the heartworm preventive Heartgard Plus (ivermectin/pyrantel) and packages Brazilian-made NexGard chewables for shipment to the United States and Canada.

Please allow 6 to 8 weeks for delivery. I have been using HEARTGARD Plus for over twenty years to prevent heartworm disease and control intestinal parasites in my patients. It has been proven to not only be a safe and effective preventive, but it is also a joy to administer as it is a tasty beef chew.

The monthly heartworm preventative we prescribe only lasts in a dog's or cat's body for one to two days, not 30 days, due to the lifestyle of the heartworm, it is only necessary for the pet to take the heartworm preventative every 30 days.

The monthly heartworm preventative we prescribe only lasts in a dog's or cat's body for one to two days, not 30 days, due to the lifestyle of the heartworm, it is only necessary for the pet to take the heartworm preventative every 30 days.