Control Status: Fentanyl-related substances are controlled in schedule I of the CSA.

Fentanyl is a synthetic opioid that is up to 50 times stronger than heroin and 100 times stronger than morphine. It is a major contributor to fatal and nonfatal overdoses in the U.S.

WARNING: ADDICTION, ABUSE, AND MISUSE; LIFE-THREATENING RESPIRATORY DEPRESSION; CYTOCHROME P450 3A4 INTERACTION; and RISKS FROM CONCOMITANT USE WITH BENZODIAZEPINES OR OTHER CNS DEPRESSANTS.

Naloxone is a life-saving medication that can reverse an overdose from opioids - including heroin, fentanyl, and prescription opioid medications - when given in time.

What is fentanyl? Pharmaceutical fentanyl is a synthetic opioid approved for treating severe pain, typically advanced cancer pain. It is 50 to 100 times more potent than morphine. It is prescribed in the form of transdermal patches or lozenges and can be diverted for misuse and abuse in the United States.

Fentanyl works by binding to the body's opioid receptors, which are found in areas of the brain that control pain and emotions. Its effects include extreme happiness, drowsiness, nausea, confusion, constipation, sedation, tolerance, addiction, respiratory depression and arrest, unconsciousness, coma, and death.

It's the deadliest drug crisis in US history. More than 100,000 Americans died from drug overdoses between August 2021 and August 2022 alone, according to Foreign Affairs. Much of this epidemic is driven by fentanyl, which now kills around 200 Americans every day.

Fentanyl in small doses is most useful for minor, but painful, surgical procedures. In addition to the analgesia during surgery, fentanyl may also provide some pain relief in the immediate postoperative period. Moderate Dose - 2 to 20 mcg/kg (0.002 to 0.02 mg/kg) (0.04 to 0.4 mL/kg).

Fentanyl is a synthetic opioid typically used to treat patients with chronic severe pain or severe pain following surgery. Fentanyl is a Schedule II controlled substance that is similar to morphine but about 100 times more potent.

What is the legal status in the Federal Control Substances Act? Fentanyl is a Schedule II narcotic under the United States Controlled Substances Act of 1970.

August 21 marks Fentanyl Prevention and Awareness Day, seeking to educate the public on the dangers of fentanyl, fake pills, and other illicit drugs, while also highlighting the difference between fentanyl poisoning and overdose.

Fentanyl may cause serious breathing problems or death if it is used by people who are not being treated with other narcotic medications or who are not tolerant to narcotic medications. Fentanyl may cause serious harm or death if used accidentally by a child or by an adult who has not been prescribed the medication.