The EpiPen® auto injector contains 2 ml of adrenaline injection 1 mg/ml in a prefilled disposable automatic injection device which is designed to deliver a single dose (0.3 ml) of 0.3 mg adrenaline when activated. After activation of the auto injector, 1.7 ml remains in the auto injector.

The Epipen was manufactured by Meridian Medical Technologies of Columbia, Maryland, for Mylan Specialty L.P., Morgantown, West Virginia (a Pfizer company). The FDA approved the product in 1987. Meridian launched the 2-Pak in 2001.

Injectable Kit

EpiPen® and EpiPen Jr® Auto-Injectors are for the emergency treatment of life-threatening allergic reactions (anaphylaxis) caused by allergens, exercise, or unknown triggers; and for people who are at increased risk for these reactions.

EpiPen, also known by its generic name as epinephrine, is a prescription-only brand name medication made by Viatris.

Once injected, epinephrine works quickly to raise blood pressure and open airways. However, one dose may not be enough for everyone. Up to 20 percent of people experiencing anaphylaxis will have what's known as a biphasic reaction, in which they are wracked with another attack hours after the first.

Epinephrine auto-injectors come in packages of two for a reason. It's estimated 15-30 percent of anaphylaxis episodes will require more than one auto-injector to stop symptoms. This is why they should remain stored together at all times.

Meridian, a subsidiary of Pfizer that manufactures EpiPen® 0.3 mg and EpiPen Jr® 0.15 mg Auto-Injectors, and the authorized generic versions of these strengths, continues to experience manufacturing constraints affecting supply.

EpiPen 2-Pak is used to treat severe allergic reactions (anaphylaxis) to insect stings or bites, foods, drugs, and other allergens. Epinephrine auto-injectors may be kept on hand for self-injection by a person with a history of severe allergic reaction.

If you or your child do not feel better or get worse, you can inject another dose of EpiPen® or EpiPen Jr® 5 to 15 minutes after the first injection. Do not inject more than 2 injections right after each other. Too much epinephrine can cause dangerously high blood pressure, stroke, or death.

St. Louis, Missouri EpiPens deliver a potentially lifesaving dose of the generic drug epinephrine via an automatic injector. They are made at a single Pfizer Inc facility near St. Louis, Missouri.

They took advantage of the fact that they basically had a monopoly and raised the prices accordingly." The public furor over the cost prompted Mylan to come out with a generic EpiPen costing $300. There are also now four other epinephrine manufacturers on the market: Kal'o, Impax Lab, Sandoz and Teva Pharmaceuticals.

EpiPen Auto-Injectors (epinephrine injections, USP, 1:1000, 0.3 mL) are available in individual cartons, NDC 49502-500-01, and as EpiPen 2-Pak®, NDC 49502-500-02, a pack that contains two EpiPen Auto-Injectors (epinephrine injections, USP, 1:1000, 0.3 mL) and one EpiPen Auto-Injector trainer device.

Each EpiPen or EpiPen Jr is a single-dose epinephrine injection for single use. Since the doses of epinephrine delivered from EpiPen or EpiPen Jr are fixed, consider using other forms of injectable epinephrine if doses lower than 0.15 mg are deemed necessary.

EPIPEN®, EPIPEN JR®, EPIPEN 2-PAK®, EPIPEN JR 2-PAK®, EPIPEN4SCHOOLS®, NEVER-SEE-NEEDLE®, LIFE HAPPENS. Be Prepared®, the EPIPEN / EPIPEN JR Logo and the Mylan Logo are registered trademarks of Mylan Inc., a Viatris Company. VIATRIS and the Viatris Logo are trademarks of Mylan Inc., a Viatris Company.

St. Louis, Missouri EpiPens deliver a potentially lifesaving dose of the generic drug epinephrine via an automatic injector. They are made at a single Pfizer Inc facility near St. Louis, Missouri.