Alka-Seltzer Plus Cold is a combination medicine used to treat headache, fever, body aches, runny or stuffy nose, sneezing, itching, watery eyes, and sinus congestion caused by allergies, the common cold, or the flu. Alka-Seltzer Plus Cold may also be used for purposes not listed in this medication guide.

Alka-Seltzer Plus Severe Cold and Flu is a combination of four medications: acetaminophen (an analgesic), chlorpheniramine (an antihistamine), dextromethorphan (a cough suppressant), and phenylephrine (a decongestant). It's used to treat symptoms from the common cold or flu and is available over the counter.

In Each Capsule: Active Ingredients: Acetaminophen (325 Mg), Pain Reliever/Fever Reducer; Chlorpheniramine Maleate (2 Mg), Antihistamine; Dextromethorphan Hydrobromide (10 Mg), Cough Suppressant; Phenylephrine Hydrochloride (5 Mg), Nasal Decongestant.

It works by reducing substances in the body that cause pain, fever, and inflammation. Chlorpheniramine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Alka-Seltzer contains three active ingredients: aspirin (acetylsalicylic acid) (ASA), sodium bicarbonate, and anhydrous citric acid. The aspirin is a pain reliever and anti-inflammatory, the sodium bicarbonate is an antacid, and the citric acid reacts with the sodium bicarbonate and water to form effervescence.

What are the active ingredients in Alka-Seltzer effervescent products? All effervescent products contain anhydrous citric acid (antacid) and sodium bicarbonate (antacid). Alka-Seltzer Original, Extra Strength and Lemon-Lime also contain aspirin (analgesic). Alka-Seltzer Gold contains potassium bicarbonate (antacid).

Adults and children age 12 years or older: The typical dose is 2 tablets, fully dissolved in one-half cup of water, by mouth every 4 hours while you're having symptoms. Don't use more than 8 tablets (4 doses) in a 24-hour period unless your provider specifically told you to do so.

Alka-Seltzer Plus Severe Cold And Cough can also worsen certain medical conditions, such as liver, kidney, or heart disease; high blood pressure; glaucoma; stomach problems; or urination problems.

ALKA-SELTZER PLUS SEVERE COLD AND FLU- acetaminophen, chlorpheniramine maleate, dextromethorphan hydrobromide, phenylephrine hydrochloride tablet, effervescent.

Drug Label Information

Adults and children age 12 years or older: The typical dose is 2 tablets, fully dissolved in one-half cup of water, by mouth every 4 hours while you're having symptoms. Don't use more than 8 tablets (4 doses) in a 24-hour period unless your provider specifically told you to do so.

Alka-Seltzer Plus Cold might make you feel drowsy or sleepy, so don't drive or operate any machinery until you know how this medication affects you. Don't drink alcohol when taking this medication because it might make you feel more drowsy or sleepy.

Alka-Seltzer is an effervescent antacid and pain reliever first marketed by the Dr. Miles Medicine Company of Elkhart, Indiana, United States.

The history of Alka Seltzer begins in Elkhart, IN, where the formula was developed in Miles Laboratories in 1931. The advertising campaign for the "new health drink" was successful and "before World War II, Miles was spending $1 million to $1.5 million a year on network radio, most of it on Alka Seltzer.

This medication is used to treat symptoms caused by too much stomach acid such as heartburn, upset stomach, or indigestion. It is an antacid that works by lowering the amount of acid in the stomach. Check the ingredients on the label even if you have used the product before.