Tylenol PM Extra Strength (acetaminophen / diphenhydramine) is a combination medication used to help relieve minor aches and pains. It also helps you sleep when your aches and pains are making it hard for you to sleep. Tylenol PM Extra Strength (acetaminophen / diphenhydramine) is available over the counter.

by Johnson & Johnson. Acetaminophen + Diphenhydramine (Tylenol PM) is used for relief of allergies, cold, and cough symptoms. Acetaminophen is in a class of medications called analgesics (pain relievers) and antipyretics (fever reducers) & Diphenhydramine is in a class of medications called antihistamines.

Generic Name: diphenhydramine-acetaminophen.

Experts say this is concerning for a number of reasons. Studies have linked the regular, long-term use of OTC sleep medicines to some potentially serious side effects. “Many OTC sleep aids - such as Benadryl and Tylenol PM - contain diphenhydramine,” says Dr.

Tylenol PM has an average rating of 5.9 out of 10 from a total of 27 reviews for the treatment of Insomnia. 52% of reviewers reported a positive experience, while 37% reported a negative experience.

It's not a good idea to take it long-term, according to our medical advisors. Tylenol PM contains two medications - the pain reliever acetaminophen and an antihistamine (diphenhydramine) to help with insomnia. High doses of acetaminophen can cause liver damage and the risk increases if you consume alcohol.

Tylenol PM, specifically, has acetaminophen (the active ingredient in Tylenol) combined with diphenhydramine. Acetaminophen, when taken in large doses, can potentially affect the liver so should be used judiciously. Benadryl, Unisom and Sominex, for example, do not contain acetaminophen, only diphenhydramine.

TYLENOL® PM Extra Strength Liquid is a pain reliever and sleep aid that helps you fall asleep fast for a better night's sleep. Provides 1,000 mg of acetaminophen & 50 mg of diphenhydramine HCI.

Advil PM does not contain acetaminophen, the active ingredient in Tylenol PM, and it's been proven that Advil PM gives you a better night's sleep than Tylenol PM because you'll spend less time lying awake with annoying aches and pains and more time asleep.

Melatonin: Melatonin is considered one of the safest over-the-counter sleep aids, with few side effects. A prescription drug called ramelteon is designed to mimic the effects of melatonin. Like melatonin, it is not considered habit-forming and it does not affect balance.

Anticholinergics Diphenhydramine (Benadryl), acetaminophen with diphenhydramine (Tylenol PM) and some muscle relaxants that contain diphenhydramine (an antihistamine) can cause confusion, constipation, dry mouth, blurry vision or urine retention in older adults. Cumulative exposure to these drugs can lead to dementia.

It's difficult to get comfortable at night in order to fall asleep. However, after taking two Tylenol PM (the recommended dose) within the hour I'm comfortable enough to doze off. I stay asleep for 6-10 hours most nights. Without it I would maybe get a few hours a night if I was lucky.

Melatonin Melatonin: Melatonin is considered one of the safest over-the-counter sleep aids, with few side effects. A prescription drug called ramelteon is designed to mimic the effects of melatonin. Like melatonin, it is not considered habit-forming and it does not affect balance.

There are several prescription sleeping pills that may be appropriate and safe pills for elderly individuals, such as zolpidem (Ambien) and eszopiclone (Lunesta).

Doxylamine What is the strongest sleep aid over the counter? Doxylamine is one of the strongest OTC sleep aids. It is an antihistamine.

In young children, this drug may cause agitation and excitement instead of drowsiness. Older adults may be more sensitive to the side effects of this drug, especially dizziness, drowsiness, confusion, constipation, or trouble urinating.