It aims to reduce depressive symptoms and prevent them from returning. Trintellix is classified as a miscellaneous antidepressant, although some classify it as an SSRI (selective serotonin reuptake inhibitor) and a serotonin receptor modulator.

Trintellix is only available as a brand-name drug. Lexapro is available as a brand-name drug and in a generic form called escitalopram. Generic Lexapro is much less expensive than Trintellix.

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Official answer. Although Trintellix is not approved for anxiety, it has been used off-label to treat generalized anxiety disorder (GAD). It appears to work best in those with severe GAD (HAMA of >25).

Manic episodes: Manic episodes may happen in people with bipolar disorder who take TRINTELLIX. Symptoms may include: greatly increased energy; racing thoughts; unusually grand ideas; talking more or faster than usual; severe problems sleeping; reckless behavior; excessive happiness or irritability.

If you don't have insurance coverage, the average cost of Trintellix you will pay is approximately $440 for a 30-day supply of the 10mg dosage. Prices may vary depending on your chosen pharmacy, with the highest price at HealthWarehouse (online), around $525, and the lowest at most major pharmacies like Walmart.

Trintellix is only available as a brand-name drug. It doesn't come in a generic version. A generic drug is an exact copy of the active drug in a brand-name medication. Generics tend to cost less than brand-name drugs.

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Preliminary study results reported the beneficial effect of treatment with Trintellix on subjective sleep and daytime sleepiness in patients with insomnia and major depressive disorder.

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There have been reports of sleepiness in some people taking Trintellix since the drug was approved. It's not known if Trintellix was the cause of this sleepiness. Additionally, tiredness could possibly be a symptom of withdrawal* if you were to suddenly stop taking Trintellix.