What is TRINTELLIX?
Trintellix is a prescription medication used to treat major depressive disorder (MDD) in adults. It contains the active ingredient vortioxetine, which is an antidepressant. Trintellix works by increasing the levels of chemicals in the brain that regulate mood, such as serotonin, norepinephrine, dopamine, and GABA.
Trintellix is classified as a miscellaneous antidepressant , although some classify it as a selective serotonin reuptake inhibitor (SSRI) and a serotonin receptor modulator. It is available as an oral tablet in strengths of 5mg, 10mg, 15mg, and 20mg.
Trintellix is not recommended for use in children and adolescents under the age of 18. It is also not recommended for those with a history of bipolar disorder or mania, as it may increase the risk of manic episodes.
Like all medications, Trintellix may cause side effects. The most common side effects include nausea, diarrhea, constipation, vomiting, and dry mouth. Trintellix may also cause dizziness, headaches, and sleep disturbances. Rare but serious side effects may include suicidal thoughts or behavior, serotonin syndrome, and bleeding problems.
It is important to inform your healthcare provider of any other medications you are taking, as Trintellix may interact with certain medications, including monoamine oxidase inhibitors (MAOIs) and serotonin and norepinephrine reuptake inhibitors (SNRIs).
Overall, Trintellix is a medication that can be effective in treating major depressive disorder in adults. It is important to follow your healthcare provider's instructions carefully when taking this medication and to report any side effects or concerns.
Frequently Asked Questions about trintellix
Trintellix is an oral tablet that is taken once a day. May be taken with or without food. Trintellix is different from other antidepressants currently on the market because it directly affects serotonin receptors as well as inhibits serotonin reuptake.
Trintellix is a doctor-prescribed SSRI-type antidepressant medication used in treating major depressive disorder in adults as young as age 18 and up. Trintellix was designed to influence the serotonin neurotransmitter, and possibly other areas of neurochemistry.
Trintellix has an average rating of 6.0 out of 10 from a total of 442 reviews on Drugs.com. 47% of reviewers reported a positive experience, while 34% reported a negative experience.
Mechanism of action1
The mechanism of the antidepressant effect of TRINTELLIX is not fully understood, but it is thought to be related to its enhancement of serotonergic activity in the central nervous system through inhibition of the reuptake of serotonin (5-HT).
Trintellix is only available as a brand-name drug. It doesn't come in a generic version. A generic drug is an exact copy of the active drug in a brand-name medication. Generics tend to cost less than brand-name drugs.
Trintellix has an average rating of 6.0 out of 10 from a total of 415 reviews for the treatment of Major Depressive Disorder. 48% of reviewers reported a positive experience, while 34% reported a negative experience.
Trintellix (vortioxetine) may increase your risk of suicidal thoughts or behavior, especially in people under the age of 25. Watch out for worsening depression or any unusual changes in your mood or behavior, especially during the first few months of treatment or with a dose change.
Common side effects of Trintellix include:
- nausea.
- diarrhea.
- dry mouth.
- constipation.
- vomiting.
- gas.
- dizziness.
- abnormal dreams.
Trintellix (vortioxetine) may increase your risk of suicidal thoughts or behavior, especially in people under the age of 25. Watch out for worsening depression or any unusual changes in your mood or behavior, especially during the first few months of treatment or with a dose change.
This medication has a boxed warning from the Food and Drug Administration (FDA). This is the strongest warning that the FDA requires. A boxed warning alerts doctors and patients about drug effects that may be dangerous. Trintellix can increase the risk of suicidal thoughts and actions in children and young adults.
Important Safety Information
TRINTELLIX may cause serious side effects, including serotonin syndrome, increased risk of bleeding, hypomania (manic episodes), discontinuation syndrome (side effects if you suddenly stop taking TRINTELLIX), visual problems, low levels of salt in your blood, or sexual problems.
Common side effects of Trintellix include:
- nausea.
- diarrhea.
- dry mouth.
- constipation.
- vomiting.
- gas.
- dizziness.
- abnormal dreams.
Important Safety Information
TRINTELLIX may cause serious side effects, including serotonin syndrome, increased risk of bleeding, hypomania (manic episodes), discontinuation syndrome (side effects if you suddenly stop taking TRINTELLIX), visual problems, low levels of salt in your blood, or sexual problems.
Trintellix is only available as a brand-name drug. It doesn't come in a generic version. A generic drug is an exact copy of the active drug in a brand-name medication. Generics tend to cost less than brand-name drugs.
It has shown a lower risk of weight gain than other antidepressant medications. In comparison with other antidepressants, Trintellix has a reduced risk of sexual dysfunction. Trintellix has similar side effects compared with other SSRI antidepressants.
TRINTELLIX may cause serious side effects, including serotonin syndrome, increased risk of bleeding, hypomania (manic episodes), discontinuation syndrome (side effects if you suddenly stop taking TRINTELLIX), visual problems, low levels of salt in your blood, or sexual problems.
