Neulasta® is a prescription medicine used to help reduce the chance of infection due to a low white blood cell count, in people with certain types of cancer (non-myeloid), who receive anti-cancer medicines (chemotherapy) that can cause fever and low white blood cell count.

The Neulasta patch, called Neulasta Onpro, is applied by a healthcare professional right after your chemotherapy infusion. The patch automatically delivers the dose of Neulasta over 45 minutes, approximately 27 hours after the patch is applied. Once the dose is complete, you remove the patch.

As of 4/14/2022, the list price for Neulasta® is $6,417.99† per dose. Neulasta® is a single dose administered once per chemotherapy cycle. Most patients do not pay the list price.

Neulasta is indicated to decrease the incidence of infection, as manifested by febrile neutropenia, in patients with non-myeloid malignancies receiving myelosuppressive anti-cancer drugs associated with a clinically significant incidence of febrile neutropenia [see Clinical Studies (14.1)].

Attach the on-body injector to the back of patient's upper arm or abdomen. The on-body injector will deploy the cannula in three minutes, even if not applied to the patient. If not on patient's body in three minutes, do not use the on-body Injector. Start again with a new Neulasta Onpro kit.

What are the ingredients in Neulasta? Each syringe contains pegfilgrastim in a sterile, clear, colorless, preservative-free solution containing acetate, sorbitol, polysorbate 20, and sodium.

Neulasta may cause serious side effects, including:

• Spleen rupture.
• A serious lung problem called Acute Respiratory Distress Syndrome (ARDS).
• Serious allergic reactions.
• Sickle cell crises.
• Kidney injury (glomerulonephritis).
• Increased white blood cell count (leukocytosis).
• Decreased platelet count (thrombocytopenia).

The Neulasta on-body injector (OBI) should be removed when the dose has been completely delivered, you should hear a long beep, the status light should be a solid green or switched off. Remove the on-body injector by grasping the edge of the adhesive pad and slowly peel it away from the skin.

From ₹3,000, chemotherapy cost per cycle may go up to ₹18,000 or beyond2 as well. Patients may typically, require 4-8 chemotherapy sessions, depending on the type and stage of the cancer.

Response and effectiveness Once administered, Neulasta takes 16 to 120 hours (an average of 24 hours) to reach its peak concentration. Neulasta is a long-lasting medication so blood levels slowly decrease over approximately 2 weeks.

You should not receive your dose of Neulasta any sooner than 24 hours after you finish receiving your chemotherapy. The on-body injector for Neulasta is programmed to deliver your dose about 27 hours after your healthcare provider places the on-body injector on your skin.

Neulasta is a man-made form of granulocyte colony-stimulating factor (G-CSF), which is made using the bacteria Escherichia coli. G-CSF is a substance produced by the body. It stimulates the growth of neutrophils (nu-tro-fils), a type of white blood cell important in the body's fight against infection.