Melatonin does not have many common side effects but there are things you can do to help cope with them:

• Feeling sleepy or tired in the daytime.
• Headache.
• Stomach ache.
• Feeling sick (nausea)
• Feeling dizzy.
• Feeling irritable or restless.
• Dry mouth.
• Dry or itchy skin.

“If melatonin for sleep isn't helping after a week or two, stop using it,” says Buenaver. “And if your sleep problems continue, talk with your health care provider. If melatonin does seem to help, it's safe for most people to take nightly for one to two months. “After that, stop and see how your sleep is,” he suggests.

Melatonin is a hormone that your brain produces in response to darkness. It helps with the timing of your circadian rhythms (24-hour internal clock) and with sleep. Being exposed to light at night can block melatonin production. Research suggests that melatonin plays other important roles in the body beyond sleep.

The usual starting dose is one 2mg slow release tablet taken 30 minutes to 1 hour before bedtime. Sometimes the dose may gradually be increased to 2 to 3 tablets before bedtime, depending on how well it works and whether you have any side effects. The maximum dose is 5 tablets (10mg) once daily.

Melatonin is generally safe for short-term use. Unlike with many sleep medications, with melatonin you are unlikely to become dependent on it, have less response to it after repeated use or experience a hangover effect. The most common melatonin side effects include: Headache.

Generally safe Your body likely produces enough melatonin for its general needs. However, evidence suggests that melatonin supplements promote sleep and are safe for short-term use. Melatonin can be used to treat delayed sleep phase and circadian rhythm sleep disorders in the blind and provide some insomnia relief.

Melatonin is generally considered safe to take every night at doses between 0.5 mg and 5 mg. A safe starting dose of melatonin is between 1 mg and 5 mg for adults. More melatonin can cause side effects, particularly in older adults. For older adults, lower doses, such as 1 mg, are usually considered enough melatonin.

Melatonin begins to have an effect within 30 minutes. You should start to feel peaceful & sleepy. Melatonin is a supplement that works with your natural sleep cycle. This is why it's important to have a relaxing environment to give yourself the best chance possible for a full night's sleep.

Your body likely produces enough melatonin for its general needs. However, evidence suggests that melatonin supplements promote sleep and are safe for short-term use. Melatonin can be used to treat delayed sleep phase and circadian rhythm sleep disorders in the blind and provide some insomnia relief.

Melatonin is generally safe for short-term use. Unlike with many sleep medications, with melatonin you are unlikely to become dependent on it, have less response to it after repeated use or experience a hangover effect. The most common melatonin side effects include: Headache.

In the United States, melatonin is available as an over-the-counter (OTC) sleep aid. You can find it at the drugstore or grocery store. The supplement will last in your body for about 5 hours. Some people need additional melatonin to regulate their circadian rhythm.

Even though melatonin is usually safe for most people to take short-term, talk to your health care provider if you are considering taking it daily for sleep issues. Also, if sleep troubles are starting to affect your daily life, talk to your doctor about your symptoms and potential treatment options.

Melatonin also plays a direct renoprotective role. Moreover, it can be helpful in almost every type of kidney injury because inflammation, apoptosis, and oxidative stress occur without regard to the mechanism. Melatonin regulates mitochondrial metabolism and ATP production and protects mitochondria.

Melatonin is relatively safe, but there are some dangers associated with taking too much. Depending on the severity of symptoms, a person may need to call 911 if they've taken large amounts of melatonin and are experiencing chest pain, extremely high blood pressure, or shortness of breath.

Melatonin can affect multiple cardiovascular functions, such as cardiac output, blood pressure, heart rate, and seasonal rhythms. The functions of melatonin are related to the activity of the melatonergic system and the suprachiasmatic nucleus (94).

But remember, melatonin is a hormone, not a sleep medication, therefore it does not induce sleep. In fact, taking a second dose late into the night may promote undesirable side effects such as extreme drowsiness the next day.