Caplyta belongs to the class of medicines known as atypical antipsychotics. Atypical means it is less likely than older antipsychotics to cause side effects, such as extrapyramidal symptoms (EPS).

What drug class is CAPLYTA? CAPLYTA belongs to a class of drugs known as atypical antipsychotics.

It works by affecting dopamine, serotonin, and glutamate in order to improve symptoms that affect mood, thoughts, and behaviors. The medication may help with some of the symptoms of schizophrenia, which can improve functioning in daily life.

Lumateperone is a medication that works in the brain to treat schizophrenia. It is also known as a second generation antipsychotic (SGA) or atypical antipsychotic.

Generic Name: lumateperone Lumateperone is used to treat certain mental/mood disorders (such as schizophrenia, episodes of depression associated with bipolar disorder). This medication helps you to think more clearly, feel less nervous, and take part in everyday life.

The trial's patients had a mean baseline MADRS of about 31, and Caplyta on average led to an additional 5.7-point reduction versus placebo. The average reduction in patients with bipolar depression and major depressive disorder was 5.7 points and 5.9 points, respectively.

Patients on CAPLYTA saw a 2.3-point reduction in reported sadness compared to 1.7-point reduction with placebo; 2.1-point reduction in apparent sadness compared to 1.7-point reduction with placebo; 1.6-point reduction in inner tension compared to 1.1-point reduction with placebo; 2.1-point reduction in reduced sleep ...

How long does it take Caplyta (lumateperone) to work? You can expect Caplyta (lumateperone) to start working in 1 to 2 weeks, but it may take several weeks until it takes full effect.

Caplyta has an average rating of 5.6 out of 10 from a total of 125 reviews on Drugs.com. 45% of reviewers reported a positive experience, while 41% reported a negative experience.

Caplyta, as an atypical antipsychotic, is currently approved in the U.S. to treat schizophrenia. It's also endorsed as a monotherapy and as an adjunctive therapy for depressive episodes associated with bipolar depression.

More common side effects of Caplyta

• sleepiness.
• nausea or vomiting.
• abnormal lab test results, such as increased levels of liver enzymes.
• fatigue.
• decreased appetite.
• dry mouth*
• dizziness*

SSRIs are the most widely prescribed type of antidepressants. They're usually preferred over other antidepressants, as they cause fewer side effects. An overdose is also less likely to be serious. Fluoxetine is probably the best known SSRI (sold under the brand name Prozac).

Research shows that combined pills with anti-androgenic progesterones (drospirenone or desogestrel) can help make mood swing side effects less intensive. Pills with these progesterones in include: Gedarel. Lucette.

The first-line medicine for patients with depression is generally a SSRI, e.g. citalopram, escitalopram, sertraline or fluoxetine (Tables 1 and 2).

Types & Choice

• Lithium. Lithium is used for the long-term treatment of mania.
• Valproate. Lithium might not work or be suitable for you to treat mania as part of bipolar disorder.
• Lamotrigine. Lamotrigine can treat bipolar disorder when depression is the main problem.
• Antipsychotics.
• Can I choose my medication?

Overview. Mood stabilizers are medications used in the treatment of bipolar disorder, where a person's mood changes from a depressed feeling to a high “manic” feeling or vice versa. These drugs can help reduce mood swings and prevent manic and depressive episodes.