What is the difference between FRONTLINE ® PLUS and FRONTLINE ® SPOT ON? Both products kill fleas and ticks on your pet, however FRONTLINE® PLUS has an advanced formula that also stops flea eggs that fall off pets from hatching in your home.

While Frontline Plus tends to be on the pricier side, the benefits that this particular flea medication provide are obvious. With two active ingredients, this product works very well to kill adult fleas while at the same time disrupt the reproductive cycle of fleas and ticks.

FRONTLINE Plus for Dogs is a fast-acting, long-lasting waterproof flea & tick topical that's proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease.

This FRONTLINE Plus Spot On Kills fleas within 24 hours of contact, it also kills by affecting the parasites' central nervous system, making fleas appear more visible before dying. This is non-systemic meaning it acts on contact, not via the pet's blood so the parasites do not need to bite the pet to be killed.

There are several Frontline products: Shield, Plus, and Gold. Our top choice for an OTC flea preventive is Frontline Plus, which also protects against chewing lice and helps control sarcoptic mange infestations.

Frontline Plus kills 100% of adult fleas on your pet within 12 hours and 100% of all ticks and chewing lice within 48 hours. Frontline Plus contains an insect growth regulator, S-methoprene, which kills flea eggs and larvae.

Frontline was first put into clinical trials in 1985 shortly after the discovery of it's active ingredient Fipronil. To it's credit Frontline has maintained the safest albeit not the most effective treatment for fleas and ticks. However, the more effective products pose a significantly greater risk to your dog.

Frontline Side Effects There are many concerns about possible side effects, the most common being skin reactions like hair loss, itching, and redness, and neurological issues like uncoordinated movement and lethargy.

Fleas and ticks are killed through contact with your dog's skin and coat so they do not need to bite to be killed. This topical defence kills parasites on contact, without the need for them to bite to be killed. Frontline kills fleas by affecting their nervous system, making them hyperactive before dying.

FRONTLINE PLUS FOR DOGS should be applied every 2 weeks for control of paralysis ticks on dogs, or every month for control of brown dog ticks. FRONTLINE SPRAY should be applied every 3 weeks for control of paralysis ticks on cats and dogs, or every month for the control of brown dog ticks.

Frontline Spray provides long-lasting, effective control of fleas and ticks on your pet. It kills up to 100% of existing fleas in less than 24 hours. Frontline Spray continues killing fleas for an entire month or more.

Incorrectly applying topical flea prevention is the most common cause for why it's not working. Topical medication should be applied directly to the skin, not to your pet's fur. You must part their hair so you can apply it to the skin.