FRONTLINE Plus for Dogs is a fast-acting, long-lasting waterproof flea & tick topical that's proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease.

Part dog's hair between shoulder blades. Place applicator tip just above the skin and squeeze. Apply entire contents of applicator in a single spot directly onto dog's skin. Do not apply on top of hair coat.

Frontline Plus for dogs is generally safe to use and causes few side effects. Mild skin irritation may occur but should clear up quickly. Additional side effects may include vomiting, diarrhea, and seizure. However, these side effects are extremely rare and tend to affect smaller dogs.

5. The active ingredients in Frontline Plus for Dogs are Fipronil 9.8%, (S)-methoprene 8.8% with 81.4% inactive ingredients. The active ingredients in Frontline Plus for Cats are Fipronil 9.8%, (S)-methoprene 11.8% with 78.4% inactive ingredients.

Best OTC topical preventive: Frontline Plus Frontline Plus has been used and trusted by pet owners for over two decades. Parasites die on contact - they do not have to bite your dog for the treatment to work.

Just one dose of FRONTLINE Plus each month protects against fleas & ticks for a full 30 days.

So I can see skin. And then we're going to apply the liquid. Directly to that skin trying to reduce the amount that is whipped away in the hair. Now it does not hurt Chloe.

Yes. FRONTLINE PLUS is water-fast. It is OK to bathe your pet before using FRONTLINE PLUS, but the coat should be completely dry prior to application. In the 48 hours immediately after treatment, do not bath, shampoo or let your dog go swimming.

Among the best flea treatments for dogs, Frontline Plus is our top nonprescription recommendation because it kills ticks and fleas, controls flea infestations, and kills chewing lice, all with one easy application. When used primarily for flea control, each dose of Frontline Plus lasts up to three months.

The reason Frontline is so expensive compared to Hartz and other brands is because Frontline does the research and changes the formula frequently to counteract immunities that may have built up. We use it on our cat who is inside/outside and she doesn't scratch.

Frontline® Plus for Cats includes the ingredients fipronil and (S)-methoprene. Frontline® Plus is used to kill fleas and prevent all flea stages from developing.

The 2 main active ingredients in all Frontline® products are fipronil and (S)-methoprene. Fipronil works by blocking certain messenger channels in the insects' nervous system, which causes overstimulation and death. (S)-methoprene is chemically similar to a naturally occurring growth hormone found in insects.

Efficacy. One study found that Frontline Plus is 100% effective in treating all life stages of fleas and ticks within 12 to 24 hours following treatment.