Simparica Trio is a veterinary medicine used to treat dogs with flea or tick infestations and roundworm or hookworm infections in the gut. At the same time, Simparica Trio is used to prevent heartworm and lungworm disease (both caused by blood worms that infect the heart and blood vessels supplying the lungs).

Generally, the Simparica Trio medication is well-tolerated amongst dogs. Side effects are uncommon but can include vomiting, diarrhea, lethargy, loss of appetite, increased thirst and itching or skin irritation.

The cumulative deaths reported to April 2021 ranged from a high of 2,627 (24%) for fluralaner (Bravecto®) to 726 (2.8%) for afoxolaner (NexGard®) and 412 (12.7%) for sarolaner (Simparica®).

For flea or tick infestations, one treatment with Simparica Trio is effective for up to 5 weeks. Further flea or tick treatment should be continued using a different veterinary medicine with a narrower range of action. To prevent lungworm and heartworm disease for one month, a single treatment is required.

Simparica kills adult fleas so fast they don't get a chance to lay eggs and reproduce. Why can I still see fleas on my dog after giving Simparica? Fleas can live in a variety of areas outside of your home as well as on other dogs that your dog may encounter.

Infected dogs should be treated with an adulticide to remove adult heartworms. SIMPARICA TRIO is not effective against adult D. immitis.

IMPORTANT SAFETY INFORMATION Simparica is for use only in dogs 6 months of age and older. Simparica may cause neurologic signs such as tremors, unsteadiness and/or seizures in dogs with or without a history of neurologic disorders.

Simparica Trio is generally well-tolerated by most dogs. However, there are some other alternative flea and tick care or preventative parasite medications that your veterinarian may recommend, including: Bravecto. Nexgard.

Shows. The number of dog owners who think otherwise. Is growing try to resuscitate him. And he was pronounced dead on arrival. Life hasn't been the same without him I mean.

NexGard Chew is also effective in killing adult fleas, so it can help reduce the risk of your dog getting flea bite dermatitis. If you're looking for a safe and effective flea and tick treatment for your dog, NexGard Chew is the way to go.

Oral preventatives containing isoxazoline (e.g. Nexgard, Simparica, Credelio, Bravecto) also do not prevent tick attachment, but they have a relatively fast tick kill time.

After you give your dog his Simparica chew the ingredient sarolaner travels in your dog's blood and quickly reaches tissue fluids just under your dog's skin. As fleas and ticks bite their nervous system becomes over-stimulated and they die.