DUPIXENT helps prevent severe asthma attacks (exacerbations) and can improve your breathing. DUPIXENT may also help reduce the amount of oral corticosteroids you need while preventing severe asthma attacks and improving your breathing. DUPIXENT is not used to treat sudden breathing problems.

Each pre-filled syringe delivers 300 mg dupilumab in 2 mL which also contains L-arginine hydrochloride (10.5 mg), L- histidine (6.2 mg), polysorbate 80 (4 mg), sodium acetate (2 mg), sucrose (100 mg), and water for injection, pH 5.9.

Dupixent (Dupilumab) First Biologic Drug Approved for Patients with Moderate-to-Severe Atopic Dermatitis. Atopic dermatitis, the most common form of eczema, is a chronic inflammatory disease that is characterized by skin rash and itching.

Dupixent has fast become a blockbuster product for both Sanofi and Regeneron since its first approval in 2017. Several rival companies, among them Pfizer, AbbVie and Eli Lilly, are developing competitors they hope are more effective against an array of conditions like eczema and several types of arthritis.

Allergic reactions. DUPIXENT can cause allergic reactions that can sometimes be severe.

• breathing problems or wheezing.
• fast pulse.
• fever.
• general ill feeling.
• swollen lymph nodes.
• swelling of the face, mouth, tongue or throat.
• hives.

Dupixent could cause ocular (eye-related) side effects, including: pink eye. blepharitis (eyelid inflammation) keratitis (inflammation of the cornea)

Many studies have reported that Dupixent does not cause any serious effects on the liver. No study has reported clinically apparent acute liver injury attributed to dupilumab therapy. Dupilumab is a human monoclonal antibody and is unlikely to damage the liver.

Studies haven't found any increased risk of cancer in people who receive Dupixent. There is an increased risk of cancer with certain immunosuppressant medications used to treat severe eczema or asthma. Immunosuppressants reduce certain functions of your immune system, which is your body's defense against disease.

Allergic reactions. DUPIXENT can cause allergic reactions that can sometimes be severe.

• breathing problems or wheezing.
• fast pulse.
• fever.
• general ill feeling.
• swollen lymph nodes.
• swelling of the face, mouth, tongue or throat.
• hives.

Dupixent's cost may also be higher because it's an injectable medication and may only be available through specialty pharmacies. And in some cases, you need to visit your doctor to receive a dose. To learn more about ways to save on the cost of Dupixent, see the “Can I get help paying for Dupixent?” section below.

As with other medications, Dupixent can interact with certain other drugs and vaccines. However, Dupixent is not known to interact with alcohol, supplements, or foods.

Dermatologists consider dupilumab to have a good safety profile and to be less likely to cause renal adverse effects. However, we describe a case in which decreased renal function became apparent after starting dupilumab treatment.

Average 12 Month Prices for Dupixent

Does Dupixent cause liver damage? Many studies have reported that Dupixent does not cause any serious effects on the liver. No study has reported clinically apparent acute liver injury attributed to dupilumab therapy. Dupilumab is a human monoclonal antibody and is unlikely to damage the liver.

Studies haven't found any increased risk of cancer in people who receive Dupixent. There is an increased risk of cancer with certain immunosuppressant medications used to treat severe eczema or asthma. Immunosuppressants reduce certain functions of your immune system, which is your body's defense against disease.

Subcutaneous Solution