Cologuard is indicated to screen adults of either sex, 45 years or older, who are at typical average risk for CRC. Cologuard is not a replacement for diagnostic colonoscopy or surveillance colonoscopy in high-risk individuals.

Cologuard vs Colonoscopy According to GI Alliance, Cologuard can miss up to 8% of colon cancer and more than 50% of pre-cancerous polyps. Stool DNA (Cologuard) testing is designed to detect and not prevent cancer. A colonoscopy is the only test that both detects and prevents colon cancer.

Couric, whose first husband Jay Monahan died of colon cancer in 1998, is the face of Exact Sciences' new “Mission to Screen” campaign that launched this week for Colon Cancer Awareness Month.

The test is done to screen for colon and rectal cancer and abnormal growths (polyps) in the colon or rectum. Your provider may suggest Cologuard testing once every 1 to 3 years starting at age 45 years. The test is recommended if you are age 45 to 75 years and have an average risk of colon cancer.

Cologuard is intended to screen adults 45 years of age and older who are at average risk for colorectal cancer by detecting certain DNA markers and blood in the stool.

For people at average risk The ACS recommends that people at average risk* of colorectal cancer start regular screening at age 45. This can be done either with a sensitive test that looks for signs of cancer in a person's stool (a stool-based test), or with an exam that looks at the colon and rectum (a visual exam).

If the Cologuard test is positive, it may mean that colon cancer or polyps are present. After a positive Cologuard test a colonoscopy is required for a definitive answer. The Cologuard test has a 13% false-positive rate, which means 1 in 10 positive tests will incorrectly identify cancer or polyps.

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In 2021, the U.S. Preventive Services Task Force issued a new recommendation that colorectal cancer screening for people at average risk should start five years sooner. The change to 45 was based on the trend of growing cases among younger adults.

How Often Should I Get a Colonoscopy? Get your first screening at age 45. If you're at average risk, you should have a colonoscopy once each decade through age 75. If you're at a higher risk for colon cancer, your doctor may recommend a colonoscopy every five years instead.

In 2021, the U.S. Preventive Services Task Force issued a new recommendation that colorectal cancer screening for people at average risk should start five years sooner. The change to 45 was based on the trend of growing cases among younger adults.

Cologuard is intended for the qualitative detection of colorectal neoplasia associated DNA markers and for the presence of occult hemoglobin in human stool. A positive result may indicate the presence of colorectal cancer (CRC) or advanced adenoma (AA) and should be followed by colonoscopy.