MOVANTIK blocks opioids from attaching to something called “mu-receptors” in your bowels - directly targeting the area impacted by opioid-induced constipation. This design helps provide relief efficiently and enable bowel movements.

What are the ingredients in MOVANTIK? Active ingredient: naloxegol oxalate Inactive ingredients: The tablet core contains mannitol, cellulose microcrystalline, croscarmellose sodium, magnesium stearate, and propyl gallate.

This medication is used to treat constipation caused by opioid medications in people with ongoing pain that is not caused by cancer. It blocks the effect of opioids on the gut without blocking the effect on pain. Naloxegol belongs to a class of drugs known as opioid antagonists.

AstraZeneca today announced that the US Food and Drug Administration (FDA) approved MOVANTIK™ (naloxegol) tablets C-II as the first once-daily oral peripherally-acting mu-opioid receptor antagonist (PAMORA) medication for the treatment of opioid-induced constipation (OIC), in adult patients with chronic, non-cancer ...

You should take MOVANTIK exactly as your health care provider tells you. Be sure to take your prescribed dose of MOVANTIK 1 time each day, on an empty stomach, at least 1 hour before your first meal of the day or 2 hours after the meal.

Movantik for Opioid-Induced Constipation User Reviews. Movantik has an average rating of 5.4 out of 10 from a total of 80 reviews for the treatment of Opioid-Induced Constipation. 44% of reviewers reported a positive experience, while 41% reported a negative experience.

The cost for Movantik oral tablet 25 mg is around $426 for a supply of 30 tablets, depending on the pharmacy you visit.

The recommended MOVANTIK dosage is 25 mg once daily in the morning. If patients are not able to tolerate MOVANTIK, reduce the dosage to 12.5 mg once daily [see Clinical Pharmacology (12.2)].

MOVANTIK is a prescription medicine used to treat constipation that is caused by prescription pain medicines called opioids, in adults with long-lasting (chronic) pain that is not caused by active cancer. Click here for the Medication Guide and full Prescribing Information for MOVANTIK.

MOVANTIK is a prescription medicine used to treat constipation that is caused by prescription pain medicines called opioids, in adults with long-lasting (chronic) pain that is not caused by active cancer. Click here for the Medication Guide and full Prescribing Information for MOVANTIK.

Severe stomach pain or diarrhea, or both severe stomach pain and diarrhea. Tear in your stomach or intestinal wall (perforation). The most common side effects of MOVANTIK include: stomach (abdomen) pain, diarrhea, nausea, gas, vomiting, and headache.

MOVANTIK is taken once a day in the morning, on an empty stomach,* for the duration of opioid treatment.

MOVANTIK is taken once a day in the morning, on an empty stomach,* for the duration of opioid treatment. In the same 2 studies, response rate for MOVANTIK was 40% to 44% with a 25 mg dose and 35% to 41% with a 12.5 mg dose.

Take this medicine on an empty stomach at least 1 hour before the first meal of the day or 2 hours after a meal. Swallow the tablet whole. Do not crush, break, or chew it. Stop taking other laxatives before starting treatment with naloxegol.