What is Simparica?
Simparica is a brand of pet medication produced by Zoetis Petcare. It is primarily used for the prevention and treatment of fleas and ticks in dogs, and is available as a chewable tablet that is intended to be taken once a month.
According to the manufacturer, a single dose of Simparica starts killing fleas within three hours and ticks within eight hours, and provides continuous protection for a full month. It is also effective against various species of ticks, including the American dog tick, the brown dog tick, and the lone star tick.
Furthermore, Simparica Trio, an advanced version of the medication also protects dogs from heartworm disease and several other types of intestinal worms.
While generally safe when used as directed, Simparica may cause side effects in some dogs, including vomiting, diarrhea, and lethargy. It is important to consult a veterinarian prior to using Simparica on your dog, and to carefully follow the dosing instructions provided.
Overall, Simparica is a widely used medication for the prevention and treatment of fleas and ticks in dogs, and may offer an effective solution for pet owners looking to keep their furry friends free of these parasites. However, pet owners should always consult with a veterinarian before administering any medication to their pets.
Frequently Asked Questions about simparica
Zoetis US
Simparica Trio® | Zoetis US.
How does Simparica Trio work? Simparica contains three active substances: sarolaner, moxidectin and pyrantel. Sarolaner acts as an 'ectoparasiticide'. This means that it kills parasites present on the skin or in the fur of animals, such as fleas and ticks.
Final Thoughts. As you can see, both Nexgard and Simparica are extremely good and effective flea and tick treatment and they do not have a major difference between them. But that being said, Simparica does kill an additional tick specie and is relatively faster in eliminating fleas and ticks.
PARSIPPANY, N.J. – May 26, 2021 – Zoetis today announced that the U.S. Food and Drug Administration (FDA) has approved a new label indication for Simparica ® (sarolaner) Chewables for the prevention of Borrelia burgdorferi infections as a result of killing Ixodes scapularis ticks (deer ticks) for dogs six months of age ...
Simparica is a veterinary medicine used to treat infestations with ticks and fleas, demodectic and sarcoptic mange (skin infestations caused by two different types of mites) and ear mite infestations in dogs. After Simparica is given its activity against ticks and fleas lasts for at least 5 weeks.
How Simparica® & Simparica Trio® Works. The active ingredient of Simparica®, sarolaner, belongs to a newer class of flea and tick preventatives called isoxazolines. Sarolaner is ingested by fleas and ticks when they bite, and works by over-exciting their nervous system, causing paralysis and death.
Simparica kills adult fleas, and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis), and the treatment and control of tick infestations [Amblyomma americanum (lone star tick), Amblyomma maculatum (Gulf Coast tick), Dermacentor variabilis (American dog tick), Ixodes scapularis ( ...
The active ingredient of Simparica®, sarolaner, belongs to a newer class of flea and tick preventatives called isoxazolines. Sarolaner is ingested by fleas and ticks when they bite, and works by over-exciting their nervous system, causing paralysis and death.
Simparica is a veterinary medicine used to treat infestations with ticks and fleas, demodectic and sarcoptic mange (skin infestations caused by two different types of mites) and ear mite infestations in dogs. After Simparica is given its activity against ticks and fleas lasts for at least 5 weeks.
Generally, the Simparica Trio medication is well-tolerated amongst dogs. Side effects are uncommon but can include vomiting, diarrhea, lethargy, loss of appetite, increased thirst and itching or skin irritation.
isoxazoline class
Sarolaner, one of the ingredients in SIMPARICA TRIO, is a member of the isoxazoline class. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a history of seizures.
Simparica Trio is considered safe for dogs as young as eight weeks old who weigh at least 2.8 pounds. However, the product has not been evaluated in breeding, pregnant, or lactating dogs.
SIMPARICA kills adult fleas, and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis), and the treatment and control of tick infestations [Amblyomma americanum (lone star tick), Amblyomma maculatum (Gulf Coast tick), Dermacentor variabilis (American dog tick), Ixodes scapularis ( ...
Simparica is a veterinary medicine used to treat infestations with ticks and fleas, demodectic and sarcoptic mange (skin infestations caused by two different types of mites) and ear mite infestations in dogs. After Simparica is given its activity against ticks and fleas lasts for at least 5 weeks.
Mode of Action
The active substance of SIMPARICA, sarolaner, is an acaricide and insecticide belonging to the isoxazoline group. Sarolaner inhibits the function of the neurotransmitter gammaaminobutyric acid (GABA) receptor and glutamate receptor, and works at the neuromuscular junction in insects.
Generally, the Simparica Trio medication is well-tolerated amongst dogs. Side effects are uncommon but can include vomiting, diarrhea, lethargy, loss of appetite, increased thirst and itching or skin irritation.
