Prevagen is a daily capsule or tablet that comes in three strengths: 10, 20, and 40 milligrams of apoaequorin. Its website says it's not meant to treat, prevent, or cure any disease. And the company that makes it says it's intended for healthy people who don't have dementia.

Apoaequorin, the active ingredient in Prevagen®, is a calcium-binding protein isolated from jellyfish Aequorea victoria and has been used for many years as a calcium indicator.

The settlement allows Quincy Bioscience to continue marketing Prevagen provided it qualifies its advertising claims with a court-approved disclaimer.

Prevagen® is made by Quincy Bioscience and was developed by scientists and University researchers in Madison, Wisconsin.

Side effects of Prevagen are not clearly noted on the product website. Instead, it suggests notifying your doctor if you're concerned about potential side effects. Adverse effects of taking apoaequorin are very rare, but research suggests they can include headache, nausea, constipation, edema and hypertension.

The bottom line. Prevagen is a dietary supplement that's advertised to help with mild memory loss. However, evidence to support its claims is questionable, and there are concerns about whether our bodies can properly absorb its unique ingredient, apoaequorin.

Jellyfish protein (apoaequorin ) is a recombinant protein originally extracted from the Aequorea victoria species of jellyfish. 1 In nature, apoaequorin produces a blue light when exposed to calcium. Today it is produced in a lab by a company called Quincy Bioscience.

Prevagen ® is an OTC brain health supplement clinically shown to be safe and to improve memory and support brain function, such as mild memory loss associated with aging.

There is little clinical evidence that Prevagen protects brain cells, or improves memory.

Quincy Bioscience Quincy Bioscience is a biotechnology company with its primary consumer product called Prevagen®, a dietary supplement designed to support brain health and to improve cognitive function.

Apoaequorin is derived from jellyfish called Aequorea victoria. A laboratory-made version of apoaequorin is the main ingredient in the over-the-counter dietary supplement called Prevagen.

Do over-the-counter supplements help improve memory loss? Basically, no. None of the supplements marketed as being helpful for memory, or helpful in reducing dementia or reducing risk of Alzheimer's disease, has been shown to be effective.