What is Humira? Humira (also know by its generic name adalimumab) is a TNF-alpha inhibitor biologic approved by the FDA in October 2005 for use in adult patients to treat active psoriatic arthritis and in January 2008 to treat moderate-to-severe psoriasis.

Humira® is a tumor necrosis factor-alpha (TNF-α) inhibitor that binds to soluble and transmembrane TNF-α. By binding TNF-α, Humira® prevents it from interacting with p55 and p75 TNF receptors found on cell surfaces.

Risk of serious infections. Taking Humira can increase your risk for severe infections. These infections may lead to a hospital stay or, in rare cases, death. They include sepsis (a type of blood infection), tuberculosis (TB), and histoplasmosis (a fungal infection that's similar to pneumonia).

Oct 2 (Reuters) - Germany's Boehringer Ingelheim on Monday launched an unbranded version of its biosimilar of AbbVie's (ABBV.N) Humira with a list price 81% cheaper than the blockbuster rheumatoid arthritis drug.

Common side effects of HUMIRA include injection site reactions (pain, redness, rash, swelling, itching, or bruising), upper respiratory infections (sinus infections), headaches, rash, and nausea. These are not all of the possible side effects with HUMIRA.

The cost for Humira subcutaneous kit (40 mg/0.4 mL) is around $7,299 for a supply of 2 kits, depending on the pharmacy you visit. Quoted prices are for cash-paying customers and are not valid with insurance plans. This price guide is based on using the Drugs.com discount card which is accepted at most U.S. pharmacies.

Through its savvy but legal exploitation of the U.S. patent system, Humira's manufacturer, AbbVie, blocked competitors from entering the market. For the next six years, the drug's price kept rising. Today, Humira is the most lucrative franchise in pharmaceutical history.

Studies show that people taking biologics like Humira have close to a two times higher risk for being diagnosed with a non-melanoma skin cancer (NMSC). Basal cell and squamous cell are the two main types. They're also the most common types of cancer in general.

Humira (adalimumab) is a medication that is used over the long-term. Your doctor will check your medication at regular intervals to be sure staying on Humira is appropriate for you. Your dose for Humira can also vary and depends on the condition being treated. However, many patients stay on Humira for many years.

The most common Humira side effects are injection site reactions, headaches, and skin rashes. But more serious side effects are also possible. These include infections and skin cancer. For many people with an autoimmune disorder, the benefits of Humira outweigh the risk of side effects.

The cost for Humira subcutaneous kit (40 mg/0.4 mL) is around $7,299 for a supply of 2 kits, depending on the pharmacy you visit. Quoted prices are for cash-paying customers and are not valid with insurance plans. This price guide is based on using the Drugs.com discount card which is accepted at most U.S. pharmacies.

The list price of originator adalimumab (Humira, AbbVie) is £352.14 per 40 mg pre-filled pen or pre-filled syringe (excluding VAT; BNF online, accessed March 2021).

Conditions HUMIRA Treats

• Moderate to Severe Rheumatoid Arthritis.
• Moderate to Severe Crohn's Disease.
• Moderate to Severe Pediatric Crohn's Disease.
• Moderate to Severe Pediatric Ulcerative Colitis.
• Psoriatic Arthritis.
• Ankylosing Spondylitis.
• Moderate to Severe Polyarticular Juvenile Idiopathic Arthritis.

The cost for Humira subcutaneous kit (40 mg/0.4 mL) is around $7,299 for a supply of 2 kits, depending on the pharmacy you visit. Quoted prices are for cash-paying customers and are not valid with insurance plans. This price guide is based on using the Drugs.com discount card which is accepted at most U.S. pharmacies.

The starting dose of HUMIRA for adult patients with plaque psoriasis is 80 mg (milligrams) on Day 1 (2 Pens). The maintenance dose is 40 mg on Day 8 (1 Pen), and 40 mg every other week thereafter.

HUMIRA may be stored at room temperature for a period up to 14 days, with protection from light. HUMIRA should be discarded if not used within the 14-day period.